Thionyl Chloride → HCID 178428764、化合物

HRID 1995362ノート

反応式

HRID 1995362 の反応式
[N+:1]([C:4]1[CH:9]=[C:8]([CH3:10])[N:7]=[C:6]([C:11]([OH:13])=O)[CH:5]=1)([O-:3])=[O:2].S(Cl)(Cl)=O.[NH2:18][C:19]1[NH:23][N:22]=[N:21][N:20]=1>>[NH:20]1[C:19]([NH:18][C:11]([C:6]2[CH:5]=[C:4]([N+:1]([O-:3])=[O:2])[CH:9]=[C:8]([CH3:10])[N:7]=2)=[O:13])=[N:23][N:22]=[N:21]1

参加物

4

反応物 3

HCID 24386Thionyl ChlorideHCID 112753916-methyl-4-nitropicolinic acidHCID 178509299HCID 178509299、化合物

生成物 1

HCID 178428764HCID 178428764、化合物収率 40.1%

実験手順

1.44 g of 4-nitro-6-methyl-2-pyridinecarboxylic acid, 27 ml of thionyl chloride and 0.79 g of 5-aminotetrazole are treated in the same manner as described in Example 1. The crude product thus obtained is washed with ethanol, whereby 0.79 g of N-(5-tetrazolyl)-4-nitro-6-methyl-2-pyridinecarboxamide is obtained.

後処理

  1. customThe crude product thus obtained
  2. washis washed with ethanol

出典と根拠

ORDレコード
ord-65871b5624ae49da81f39eef8fbc239d
出典データセット
uspto-grants-1983_09
特許番号
US04404214

反応ノート

読み込み中…