Hydrochloric Acid → HCID 13218906、化合物
反応式
S([O-])([O-])=O.[Na+].[Na+].F[S:8]([C:11]1[CH:17]=[C:16]([Br:18])[CH:15]=[C:14]([Br:19])[C:12]=1[NH2:13])(=[O:10])=[O:9].Cl>O>[NH2:13][C:12]1[C:14]([Br:19])=[CH:15][C:16]([Br:18])=[CH:17][C:11]=1[S:8]([OH:10])=[O:9]参加物
5
反応条件
- 温度
- 70 °C
実験手順
A mixture of sodium sulfite (Na2SO3 ; 20.2 g; 0.16 mol) and water (100 ml) is stirred and heated to 70° C. and 2-fluorosulfonyl-4,6-dibromoaniline (13.3 g; 0.04 mol) is added at once. The reaction mixture cools down somewhat and is reheated to 70° C. and maintained at that temperature for 20 hours. The reaction mixture is then cooled down, acidifed with 10% hydrochloric acid to yield a white precipitate. The precipitate is filtered, washed with water and dried to afford 10 g of title product, m.p. 112° C. (decomposed).
後処理
- customis reheated to 70° C.
- temperaturemaintained at that temperature for 20 hours
- temperatureThe reaction mixture is then cooled down
- customto yield a white precipitate
- filtrationThe precipitate is filtered
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-e54fa32ba2494953a21dbbca795e89a1
- 出典データセット
- uspto-grants-1983_09
- 特許番号
- US04404402
反応ノート
読み込み中…