N-(2-methoxy-5-nitrophenyl)methanesulfonamide → N-(5-amino-2-methoxyphenyl)methanesulfonamide
反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-])=O)=[CH:5][C:4]=1[NH:12][S:13]([CH3:16])(=[O:15])=[O:14]>CO.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH2:9])=[CH:5][C:4]=1[NH:12][S:13]([CH3:16])(=[O:15])=[O:14]参加物
4
実験手順
A solution of 2-Methoxy-5-nitro-methanesulfonylaminobenzene (1 g) in methanol (20 ml) containing palladium on carbon (10%, 100 mg) was stirred at RT under hydrogen for 48 h. The mixture was filtered through celite then evaporated to give 2-methoxy-5-amino-methanesulfonylaminobenzene as a brown gum. This was used without purification in the following reaction.
後処理
- filtrationThe mixture was filtered through celite
- customthen evaporated
出典と根拠
- ORDレコード
- ord-8b2221c0082a4c95abf5c3c40f2e6318
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07745490B2
反応ノート
読み込み中…