Triethyl phosphite → 5-(Diethylphosphono)pentyl acetate

反応式

[C:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9]Br)(=[O:3])[CH3:2].[P:11]([O:18]CC)([O:15][CH2:16][CH3:17])[O:12][CH2:13][CH3:14]>>[C:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][P:11]([O:15][CH2:16][CH3:17])([O:12][CH2:13][CH3:14])=[O:18])(=[O:3])[CH3:2]

参加物

反応物 2

HCID 31215Triethyl phosphite

HCID 851405-Bromopentyl acetate

生成物 1

HCID 196892225-(Diethylphosphono)pentyl acetate

実験手順

100.34 g (0.48 mol) of 5-bromopentyl acetate were heated at 150° C. for 8 hours with 79.8 g (0.048 mol) of triethyl phosphite while stirring and passing in nitrogen. The mixture was then fractionally distilled under reduced pressure.

後処理

distillationThe mixture was then fractionally distilled under reduced pressure

出典と根拠

ORDレコード: ord-37e8c73db5a4451484b91a4dd3cc9bb3
出典データセット: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05728686

反応ノート

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