tert-Butyl (3R)-3-(hydroxymethyl)pyrrolidine-1-carboxylate → tert-butyl 3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidine-1-carboxylate
反応式
[CH3:1][n:2]1[n:17][cH:16][c:4]([NH:5][c:6]2[n:15][c:14]([c:9]3[c:8](Cl)[n:7]2)[nH:13][cH:12][c:10]3[Cl:11])[cH:3]1.[CH3:18][C:19]([O:22][C:23]([N:25]1[CH2:31][CH:28]([CH2:29][OH:30])[CH2:27][CH2:26]1)=[O:24])([CH3:21])[CH3:20]>>[CH3:1][n:2]1[n:17][cH:16][c:4]([NH:5][c:6]2[n:15][c:14]([c:9]3[c:8]([O:30][CH2:29][CH:28]4[CH2:31][N:25]([C:23]([O:22][C:19]([CH3:21])([CH3:20])[CH3:18])=[O:24])[CH2:26][CH2:27]4)[n:7]2)[nH:13][cH:12][c:10]3[Cl:11])[cH:3]1参加物
7
