Acetonitrile → Tert-butyl 4-{[(7-fluoro-3,4-dioxo-3,4-dihydronaphthalen-1-yl)thio]methyl}-4-hydroxypiperidine-1-carboxylate

反応式

[CH3:30][C:31]#[N:32].[F:17][c:18]1[cH:19][c:20]2[c:25]([cH:26][cH:27]1)[C:24](=[O:28])[C:23](=[O:29])[CH:22]=[CH:21]2.[OH:1][C:2]1([CH2:15][SH:16])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1>>[OH:1][C:2]1([CH2:15][S:16][C:21]2=[CH:22][C:23](=[O:29])[C:24](=[O:28])[c:25]3[c:20]2[cH:19][c:18]([F:17])[cH:27][cH:26]3)[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1

参加物

反応物 3

HCID 6342Acetonitrile

HCID 53438219Tert-butyl 4-hydroxy-4-(mercaptomethyl)piperidine-1-carboxylate

HCID 576620196-Fluoronaphthalene-1,2-dione

生成物 1

HCID 67439097Tert-butyl 4-{[(7-fluoro-3,4-dioxo-3,4-dihydronaphthalen-1-yl)thio]methyl}-4-hydroxypiperidine-1-carboxylate

出典と根拠

ORDレコード: ord-4fa01ca4a6e04272b8f07ae62e60fa67
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…