Tetrahydrofuran → (4-methoxycarbonylphenyl) 4-[[(2-methylpropan-2-yl)oxycarbonyl-(1-naphthalen-1-ylethyl)amino]methyl]-3-phenylpiperidine-1-carboxylate

HRID 203020

反応式

HRID 203020 の反応式
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH2:8][CH:9]1[CH:10]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:11][NH:12][CH2:13][CH2:14]1)[CH:21]([CH3:22])[c:23]1[cH:24][cH:25][cH:26][c:27]2[cH:28][cH:29][cH:30][cH:31][c:32]12)=[O:33].[CH2:55]1[O:56][CH2:57][CH2:58][CH2:59]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[Cl:41][C:42](=[O:43])[O:44][c:45]1[cH:46][cH:47][c:48]([C:49](=[O:50])[O:51][CH3:52])[cH:53][cH:54]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH2:8][CH:9]1[CH:10]([c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:11][N:12]([C:42](=[O:43])[O:44][c:45]2[cH:46][cH:47][c:48]([C:49](=[O:50])[O:51][CH3:52])[cH:53][cH:54]2)[CH2:13][CH2:14]1)[CH:21]([CH3:22])[c:23]1[cH:24][cH:25][cH:26][c:27]2[cH:28][cH:29][cH:30][cH:31][c:32]12)=[O:33]

参加物

5

反応物 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 854163Methyl 4-[(chlorocarbonyl)oxy]benzoateHCID 72536010tert-butyl N-(1-naphthalen-1-ylethyl)-N-[(3-phenylpiperidin-4-yl)methyl]carbamate

生成物 1

HCID 178498298(4-methoxycarbonylphenyl) 4-[[(2-methylpropan-2-yl)oxycarbonyl-(1-naphthalen-1-ylethyl)amino]methyl]-3-phenylpiperidine-1-carboxylate

出典と根拠

ORDレコード
ord-c2d0bded4f094b059bd7e72a883ccef6
出典データセット
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

関連ノート

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