Methyl iodide → HCID 69041534、化合物
反応式
[CH3:1][O:2][C:3]1[CH:21]=[C:20]([CH:22]=[C:23]2[S:27][C:26](=[S:28])[NH:25][C:24]2=[O:29])[CH:19]=[CH:18][C:4]=1[O:5][C:6]1[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[CH:8][C:7]=1[C:14]([F:17])([F:16])[F:15].[CH3:30]I.[Al]>CN(C=O)C>[CH3:1][O:2][C:3]1[CH:21]=[C:20]([CH:22]=[C:23]2[S:27][C:26]([S:28][CH3:30])=[N:25][C:24]2=[O:29])[CH:19]=[CH:18][C:4]=1[O:5][C:6]1[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[CH:8][C:7]=1[C:14]([F:17])([F:16])[F:15]参加物
5
実験手順
To a solution of 4-[2-Methoxy-4-(4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-phenoxy]-3-trifluoromethyl-benzonitrile (500 mg, 1.15 mmol) in DMF (5 mL) was added CH3I (15 mL) and the solution was heated to 40° C. in an aluminum heating block for 8 h. The solvent was concentrated in vacuo to afford the product. 1H NMR (400 Hz, CDCl3) δ 7.97 (bs, 1H), 7.68 (dd, 1H), 7.63 (s, 1H), 7.17 (m, 3H), 6.77 (d, 1H), 3.08 (s, 3H), 2.95 (s, 3H).