4-(benzylamino)tetrahydro-2H-thiopyran 1,1-dioxide → 2H-Thiopyran-4-amine, tetrahydro-, 1,1-dioxide

HRID 2040157ノート

反応式

HRID 2040157 の反応式
C([NH:8][CH:9]1[CH2:14][CH2:13][S:12](=[O:16])(=[O:15])[CH2:11][CH2:10]1)C1C=CC=CC=1.[H][H]>[OH-].[OH-].[Pd+2].C(O)C>[O:15]=[S:12]1(=[O:16])[CH2:13][CH2:14][CH:9]([NH2:8])[CH2:10][CH2:11]1

参加物

5

反応物 2

HCID 247300404-(benzylamino)tetrahydro-2H-thiopyran 1,1-dioxideHCID 178418361HCID 178418361、化合物

生成物 1

HCID 4188082H-Thiopyran-4-amine, tetrahydro-, 1,1-dioxide

試薬・触媒・溶媒 2

HCID 9942167Palladium hydroxide触媒HCID 702Ethanol溶媒

実験手順

N-Benzyl-1,1-dioxotetrahydro-2H-thiopyran-4-amine (2.00 g) was added to ethanol (40 mL) in a pressure bottle. Palladium hydroxide on carbon (0.587 g) was added and the solution was stirred under 30 psi of hydrogen at room temperature for 2 hours. The mixture was filtered though a nylon membrane and the solvent was removed under vacuum.

後処理

  1. filtrationThe mixture was filtered though a nylon membrane
  2. customthe solvent was removed under vacuum

出典と根拠

ORDレコード
ord-31efe25f227f4fcc9fd7ff039cc5a478
出典データセット
uspto-grants-2013_11
特許番号
US08580794B2

反応ノート

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