Ethyl Acetate → 6-methoxy-N1-methylbenzene-1,2-diamine

HRID 2045813ノート

反応式

HRID 2045813 の反応式
[CH3:1][O:2][C:3]1[C:4]([N+:11]([O-])=O)=[C:5]([NH:9]C)[CH:6]=[CH:7][CH:8]=1.[C:14](OCC)(=O)C>[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([NH2:9])[C:4]=1[NH:11][CH3:14]

参加物

4

反応物 2

HCID 8857Ethyl AcetateHCID 580715913-methoxy-N-methyl-2-nitroaniline

生成物 1

HCID 596353856-methoxy-N1-methylbenzene-1,2-diamine

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

7.4 g (3-methoxy-2-nitrophenyl)-methylamine are suspended in 150 ml of ethyl acetate and hydrogenated with 1 g Pd/C 10% at a pressure of 50 psi and at ambient temperature. After 4.5 hours the catalyst is suction filtered and the filtrate is evaporated to dryness. 5.9 g of the product are obtained as an oil.

後処理

  1. filtrationsuction filtered
  2. customthe filtrate is evaporated to dryness

出典と根拠

ORDレコード
ord-6b92e237f24343b2a66c55d8a57cc8e8
出典データセット
uspto-grants-2013_11
特許番号
US08592400B2

反応ノート

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