Methanol → 4-(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-ylamino)-2-fluoro-5-methoxybenzoic acid

HRID 204868

反応式

[CH3:37][OH:38].[CH3:3][O:4][C:5]([c:6]1[c:7]([F:35])[cH:8][c:9]([NH:14][c:15]2[n:16][cH:17][c:18]3[c:19]([n:34]2)[N:20]([CH:29]2[CH2:30][CH2:31][CH2:32][CH2:33]2)[CH2:21][C:22]([F:27])([F:28])[C:23](=[O:26])[N:24]3[CH3:25])[c:10]([O:12][CH3:13])[cH:11]1)=[O:36].[Na+:2].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1.[OH-:1]>>[O:4]=[C:5]([c:6]1[c:7]([F:35])[cH:8][c:9]([NH:14][c:15]2[n:16][cH:17][c:18]3[c:19]([n:34]2)[N:20]([CH:29]2[CH2:30][CH2:31][CH2:32][CH2:33]2)[CH2:21][C:22]([F:27])([F:28])[C:23](=[O:26])[N:24]3[CH3:25])[c:10]([O:12][CH3:13])[cH:11]1)[OH:36]