Ethyl 1-benzyl-4-methylpiperazine-2-carboxylate → Ethyl 4-methylpiperazine-2-carboxylate
反応式
C([N:8]1[CH2:13][CH2:12][N:11]([CH3:14])[CH2:10][CH:9]1[C:15]([O:17][CH2:18][CH3:19])=[O:16])C1C=CC=CC=1>[Pd]>[CH3:14][N:11]1[CH2:12][CH2:13][NH:8][CH:9]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH2:10]1参加物
3
実験手順
13.1 g. of 1-benzyl-4-methylpiperazine-2-carboxylic acid, ethyl ester in 100 ml. of absolute alcohol and 3 g. of palladium on charcoal are shaken at room temperature and 50 psi for 41/2 hours. The catalyst is filtered off and the residue is distilled to obtain 4-methylpiperazine-2-carboxylic acid, ethyl ester, b.p. 0.3 mm 84°-86°.
後処理
- custom2 hours
- filtrationThe catalyst is filtered off
- distillationthe residue is distilled
出典と根拠
- ORDレコード
- ord-046bc07a9dda4d92858229e36825253a
- 出典データセット
- uspto-grants-1980_04
- 特許番号
- US04198509
反応ノート
読み込み中…