3-Aminophenol → 3-(3-Hydroxyanilino)propane-1-sulfonic acid
反応式
[NH2:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.[CH2:9]1[S:13](=[O:15])(=[O:14])[O:12][CH2:11][CH2:10]1>C(O)C>[S:13]([CH2:9][CH2:10][CH2:11][NH:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1)([OH:15])(=[O:14])=[O:12]参加物
4
実験手順
In 3 liters of ethanol were dissolved 330 g of m-amino-phenol and the resulting solution was boiled under reflux and to this solution were added 360 g of propanesultone all together. Continuation of the reflux yielded gradually white powdery crystal. After refluxing for 5 hours, the reaction solution was cooled with ice and the yielded white powdery crystal was collected by filtration and washed several times with ethanol. The yield was 146 g and the melting point was above 250° C.
後処理
- temperatureunder reflux and to this solution
- customContinuation of the reflux yielded gradually white powdery crystal
- temperatureAfter refluxing for 5 hours
- temperaturethe reaction solution was cooled with ice
- filtrationthe yielded white powdery crystal was collected by filtration
- washwashed several times with ethanol
出典と根拠
- ORDレコード
- ord-da78ed19e9f64e088dfa200300f91d85
- 出典データセット
- uspto-grants-1980_04
- 特許番号
- US04200466
反応ノート
読み込み中…