1-Butanol, 2-methyl-, 1-(4-methylbenzenesulfonate) → Methyl-2-butylmercapto-4-catechol

HRID 2050530ノート

反応式

HRID 2050530 の反応式
[OH:1][C:2]1[CH:3]=[C:4]([S:9][C:10](=N)N)[CH:5]=[CH:6][C:7]=1[OH:8].C[O-].[Na+].[Na].S(C1C=CC(C)=CC=1)(O[CH2:21][CH:22](C)[CH2:23][CH3:24])(=O)=O>CO>[CH3:21][CH:22]([CH2:23][CH3:24])[CH2:10][S:9][C:4]1[CH:3]=[C:2]([OH:1])[C:7](=[CH:6][CH:5]=1)[OH:8]

参加物

6

反応物 4

HCID 3011991-Butanol, 2-methyl-, 1-(4-methylbenzenesulfonate)HCID 5268842S-(3,4-dihydroxyphenyl)-isothioureaHCID 5360545SodiumHCID 10942334Sodium Methoxide

生成物 1

HCID 127575Methyl-2-butylmercapto-4-catechol

試薬・触媒・溶媒 1

HCID 887Methanol溶媒4 回

実験手順

22 g (0.1 mole) of S-(3,4-dihydroxyphenyl)-isothiourea were dissolved in 50 ml of anhydrous methanol in a 1 litre flask equipped with a magnetic stirrer and under a nitrogen flow. The solution was heated and a solution of sodium methoxide containing 9.2 g of sodium (4 equivalents) in 150 ml of anhydrous methanol was added. 24.2 g (0.1 mole) of 2-methylbutyl tosylate in solution in 50 ml of methanol were poured into the reaction mixture at the boiling point of methanol.

後処理

  1. customequipped with a magnetic stirrer and under a nitrogen flow
  2. temperatureThe solution was heated

出典と根拠

ORDレコード
ord-6ea91609a69b4984835986877a1b21d6
出典データセット
uspto-grants-1991_05
特許番号
US05013756

反応ノート

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