Triethylamine → Isopentyl acrylate
反応式
[CH3:1][CH:2]([CH3:6])[CH2:3][CH2:4][OH:5].[C:7](Cl)(=[O:10])[CH:8]=[CH2:9].C(N(CC)CC)C>ClCCl>[C:7]([O:5][CH2:4][CH2:3][CH:2]([CH3:6])[CH3:1])(=[O:10])[CH:8]=[CH2:9]参加物
5
実験手順
To a stirred solution of 3-methyl butanol (2.0 g, 22.6 mmol) and acryloyl chloride (2.05 g, 22.6 mmol) in dichloromethane (5 ml) at 0° C. is added dropwise triethylamine (3.2 ml, 22.7 mmol). The solution is stirred for 30 minutes at room temperature and then concentrated to a residue. The residue is washed with hexanes (2×10 ml) and the resultant combined organics are concentrated and filtered through a plug of silica to give 3.0 g of 3-methylbutyl acrylate as an oil, 93% yield.
後処理
- concentrationconcentrated to a residue
- washThe residue is washed with hexanes (2×10 ml)
- concentrationthe resultant combined organics are concentrated
- filtrationfiltered through a plug of silica
出典と根拠
- ORDレコード
- ord-2007a2004cb3479abe38f60a6f45bce0
- 出典データセット
- uspto-grants-1991_05
- 特許番号
- US05019583
反応ノート
読み込み中…