Potassium Carbonate → 2-[(4-Fluorophenyl)methyl]oxirane
反応式
ClC1C=C(C(OO)=[O:9])C=CC=1.[F:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][CH:20]=[CH2:21])=[CH:15][CH:14]=1.C(=O)([O-])[O-].[K+].[K+]>ClCCl>[F:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][CH:20]2[CH2:21][O:9]2)=[CH:15][CH:14]=1参加物
5
実験手順
To a stirred mixture of 86 parts of 3-chlorobenzeneperoxoic acid and 650 parts of dichloromethane are added dropwise (slowly) 53 parts of 1-fluoro-4-(2-propenyl)benzene. Upon completion, stirring is continued overnight at room temperature. Then there are added dropwise 92 parts of a potassium carbonate solution and the layers are separated. The organic phase is washed with a sodium bisulfite solution, dried, filtered and evaporated, yielding 58.4 parts (98.5%) of 2-(4-fluorophenylmethyl)oxirane as an oily residue.
後処理
- customthe layers are separated
- washThe organic phase is washed with a sodium bisulfite solution
- customdried
- filtrationfiltered
- customevaporated
出典と根拠
- ORDレコード
- ord-665b3b5125044a568a7c0edd67b5e1fa
- 出典データセット
- uspto-grants-1980_01
- 特許番号
- US04181664
反応ノート
読み込み中…