Methyl iodide → HCID 178503857、化合物
反応式
[CH3:1][N:2]1[CH:6]=[CH:5][N:4]=[C:3]1[NH:7][C:8]([NH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[S:9].[CH3:17][I:18]>CO>[IH:18].[CH3:1][N:2]1[CH:6]=[CH:5][N:4]=[C:3]1[NH:7][C:8]([S:9][CH3:17])=[N:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1参加物
4
実験手順
A solution of 3.0 g (0.013 mole) of N-(1-methylimidazol-2-yl)-N'-phenylthiourea in 50 ml of methanol is added 2.13 g (0.015 mole) of methyl iodide. The solution is heated under reflux for 2 hr, the solvent is evaporated and the residue is recrystallized from acetone-ether to give methyl N-(1-methylimidazol-2-yl)-N'-phenylcarbamimidothioate hydroiodide; m.p. 115°-118° C.
後処理
- temperatureThe solution is heated
- temperatureunder reflux for 2 hr
- customthe solvent is evaporated
- customthe residue is recrystallized from acetone-ether
出典と根拠
- ORDレコード
- ord-400c710788dd4492a1beb4781e19078d
- 出典データセット
- uspto-grants-1980_01
- 特許番号
- US04182865
反応ノート
読み込み中…