Hydrochloric Acid → 4-Decyloxybenzyl alcohol

HRID 2052478

反応式

HRID 2052478 の反応式
B.[CH2:2]([O:12][C:13]1[CH:21]=[CH:20][C:16]([C:17](O)=[O:18])=[CH:15][CH:14]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].Cl>O1CCCC1.O>[CH2:2]([O:12][C:13]1[CH:14]=[CH:15][C:16]([CH2:17][OH:18])=[CH:20][CH:21]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

参加物

6

反応物 3

HCID 313Hydrochloric AcidHCID 6331BoraneHCID 1385274-(Decyloxy)benzoic acid

生成物 1

HCID 130796524-Decyloxybenzyl alcohol

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 8028Tetrahydrofuran溶媒2 回

実験手順

To 100 ml. of 1.0 M borane in tetrahydrofuran cooled in an ice bath under nitrogen is added dropwise, 27.8 g. of p-decyloxybenzoic acid in 300 ml. of tetrahydrofuran over a period of 45 minutes. The mixture is stirred at room temperature for 6 hours and poured onto ice, diluted with water and 10 ml. of concentrated hydrochloric acid. The mixture is filtered and the solid washed with water to give white crystals. Recrystallization from ethanol gives white plates, m.p. 57.5°-59° C.

後処理

  1. additionis added dropwise
  2. additionpoured onto ice
  3. filtrationThe mixture is filtered
  4. washthe solid washed with water
  5. customto give white crystals
  6. customRecrystallization from ethanol
  7. customgives white plates, m.p. 57.5°-59° C.

出典と根拠

ORDレコード
ord-d5ac188512f64d4ea08b45ba858c1445
出典データセット
uspto-grants-1980_01
特許番号
US04185115

関連ノート

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