Borane → [4-(Tridecyloxy)phenyl]methanol

HRID 2052489ノート

反応式

HRID 2052489 の反応式
B.[CH2:2]([O:15][C:16]1[CH:24]=[CH:23][C:19]([C:20](O)=[O:21])=[CH:18][CH:17]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]>O1CCCC1>[CH2:2]([O:15][C:16]1[CH:17]=[CH:18][C:19]([CH2:20][OH:21])=[CH:23][CH:24]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

参加物

4

反応物 2

HCID 6331BoraneHCID 202434544-(Tridecyloxy)benzoic acid

生成物 1

HCID 13079696[4-(Tridecyloxy)phenyl]methanol

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

To 200 ml. of 1.0 M borane in tetrahydrofuran, chilled in an ice bath is added dropwise over 30 minutes 32.0 g. of p-tridecyloxybenzoic acid in 450 ml. of tetrahydrofuran. After 22 hours at room temperature, the mixture is poured onto ice. After the ice melts, the solid is filtered and washed with water to give white crystals, m.p. 72°-75° C. Recrystallization from ethanol gives white crystals, m.p. 74°-75° C.

後処理

  1. additionis added dropwise over 30 minutes 32.0 g
  2. additionthe mixture is poured onto ice
  3. filtrationthe solid is filtered
  4. washwashed with water
  5. customto give white crystals, m.p. 72°-75° C
  6. customRecrystallization from ethanol
  7. customgives white crystals, m.p. 74°-75° C.

出典と根拠

ORDレコード
ord-f2e53cf0879749c7910cf8ba228c9ebf
出典データセット
uspto-grants-1980_01
特許番号
US04185115

反応ノート

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