HCID 11586634、化合物 → HCID 11528683、化合物
反応式
[CH3:1][C@H:2]([CH2:9][O:10][CH:11]1[CH2:16][CH2:15][CH2:14][CH2:13][O:12]1)[CH2:3][C:4]#[C:5][CH:6]([OH:8])[CH3:7]>C1COCC1.[O-2].[O-2].[Mn+4]>[CH3:1][C@H:2]([CH2:9][O:10][CH:11]1[CH2:16][CH2:15][CH2:14][CH2:13][O:12]1)[CH2:3][C:4]#[C:5][C:6](=[O:8])[CH3:7]参加物
4
実験手順
A 300 g (1.3255 mol) solution of (2RS,6S)-6-methyl-7-[(RS)-(3,4,5,6-tetrahydro-2H-pyran-2-yl)oxy]hept-3-in-2-ol, dissolved in 600 ml of THF, is added by stirring to a suspension of 1500 g manganese dioxide in 2250 ml of THF, and stirring is continued at room temperature for 48 hours. The suspension is then filtered over silica gel and the solvent is removed in vacuo. 280 g of the product is obtained.
後処理
- additionis added
- filtrationThe suspension is then filtered over silica gel
- customthe solvent is removed in vacuo
出典と根拠
- ORDレコード
- ord-5d2de440f4934a1c861e482e9594be9f
- 出典データセット
- uspto-grants-2008_02
- 特許番号
- US07326798B2
反応ノート
読み込み中…