反応式
[CH3:1][C@H:2]1[NH:7][CH2:6][CH2:5][N:4]([C:8]2[CH:9]=[CH:10][C:11]3[CH2:12]O[CH2:14][C:15]4[C:16]=3[C:17]=2[CH:18]=[CH:19][CH:20]=4)[CH2:3]1.BrC1C=CC2C[S:27]CC3C=2C=1C=CC=3>>[CH3:1][C@H:2]1[NH:7][CH2:6][CH2:5][N:4]([C:8]2[CH:9]=[CH:10][C:11]3[CH2:12][S:27][CH2:14][C:15]4[C:16]=3[C:17]=2[CH:18]=[CH:19][CH:20]=4)[CH2:3]1参加物
3
実験手順
The procedure used for the synthesis of (3R)-3-methyl-1-(1H,3H-naphtho[1,8-cd]pyran-6-yl)piperazine (Example 5b)) was followed, using 6-bromo-1H,3H-naphtho[1,8-cd]thiopyran as starting material and making non-critical variations, to obtain the title compound (3R)-3-methyl-1-(1H,3H-naphtho[1,8-cd]thiopyran-6-yl)piperazine as brown solid.
出典と根拠
- ORDレコード
- ord-2a669c62074d4c03baaea38a701ea01b
- 出典データセット
- uspto-grants-2008_02
- 特許番号
- US07335660B2
関連ノート
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