Peracetic Acid → 2H-Pyran-2-one, tetrahydro-4,4,6(or 4,6,6)-trimethyl-

HRID 2057689ノート

反応式

HRID 2057689 の反応式
[CH3:1][C:2]1(C)[CH2:6][CH:5](C)[CH2:4][C:3]1=O.[C:10]([O-:13])(=[O:12])[CH3:11].[Na+].C(OO)(=O)C.C(=O)([O-])O.[Na+]>C(Cl)(Cl)Cl>[CH3:1][C:2]1([CH3:6])[CH2:3][CH:4]([CH3:5])[O:12][C:10](=[O:13])[CH2:11]1

参加物

6

反応物 4

HCID 6585Peracetic AcidHCID 1196322,2,4-TrimethylcyclopentanoneHCID 516892Sodium BicarbonateHCID 517045Sodium Acetate

生成物 1

HCID 1728432H-Pyran-2-one, tetrahydro-4,4,6(or 4,6,6)-trimethyl-

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒

実験手順

3.84 gm of 2,2,4-trimethyl-cyclopentanone were dissolved in 50 ml of chloroform and cooled in the ice bath. At 0° C., a solution of 0.2 gm of sodium acetate in 11.4 gm of a 40% aqueous peracetic acid was added. The reaction mixture was stirred for 18 hours at room temperature, then neutralized with a sodium hydrogen carbonate solution. The organic phase was separated, dried and concentrated. By distillation, 3.4 gm of 4,6,6-trimethyl-tetrahydropyran-2 -one (I) were recovered with the following characteristics:

後処理

  1. customThe organic phase was separated
  2. customdried
  3. concentrationconcentrated
  4. distillationBy distillation, 3.4 gm of 4,6,6-trimethyl-tetrahydropyran-2 -one (I)
  5. customwere recovered with the following characteristics

出典と根拠

ORDレコード
ord-f4c5da2e4ae04ed0b609208c314dfbb7
出典データセット
uspto-grants-1980_07
特許番号
US04212773

反応ノート

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