Potassium Permanganate → 5-Butyryl-6-methoxy-1-methyl-benzimidazole-2-carboxylic acid

反応式

[C:1]([C:6]1[C:17]([O:18][CH3:19])=[CH:16][C:9]2[N:10]([CH3:15])[C:11]([CH2:13][OH:14])=[N:12][C:8]=2[CH:7]=1)(=[O:5])[CH2:2][CH2:3][CH3:4].[Mn]([O-])(=O)(=O)=[O:21].[K+]>>[C:1]([C:6]1[C:17]([O:18][CH3:19])=[CH:16][C:9]2[N:10]([CH3:15])[C:11]([C:13]([OH:21])=[O:14])=[N:12][C:8]=2[CH:7]=1)(=[O:5])[CH2:2][CH2:3][CH3:4]

参加物

反応物 2

HCID 516875Potassium Permanganate

HCID 130606855-Butyryl-6-methoxy-1-methyl-benzimidazole-2-methanol

生成物 1

HCID 128066625-Butyryl-6-methoxy-1-methyl-benzimidazole-2-carboxylic acid

実験手順

In a manner analogous to that described in Example 12, 5.2 g of 5-butyryl-6-methoxy-1-methyl-benzimidazole-2-methanol are oxidised with 4.5 g of potassium permanganate to give 5-butyryl-6-methoxy-1-methyl-benzimidazole-2-carboxylic acid with a melting point above 85° (decomposition)

出典と根拠

ORDレコード: ord-7ff9a5e9ea444aa8be8e3bb0e8883874
出典データセット: uspto-grants-1980_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04213993

反応ノート

読み込み中…

参加物