Imidazole → 1-Cyclooctylmethylimidazole

HRID 2058442ノート

反応式

HRID 2058442 の反応式
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.[Na].Br[CH2:8][CH:9]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1>C(O)C>[CH:9]1([CH2:8][N:1]2[CH:5]=[CH:4][N:3]=[CH:2]2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

参加物

5

反応物 3

HCID 795ImidazoleHCID 5360545SodiumHCID 18459730(Bromomethyl)cyclooctane

生成物 1

HCID 205502381-Cyclooctylmethylimidazole

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Imidazole (2.0 g, 0.03 mol) was added to a solution of sodium (0.7 g, 0.03 mol) in dry ethanol (50 ml). The mixture was stirred and heated to boiling when bromomethylcyclooctane (5.5 g, 0.027 mol) was added dropwise. Following the addition, the reaction mixture was stirred and boiled for 15 h.

後処理

  1. temperatureheated
  2. additionwas added dropwise
  3. additionthe addition
  4. stirringthe reaction mixture was stirred

出典と根拠

ORDレコード
ord-17299225e1134e1b85d1cdd3e88ce6e3
出典データセット
uspto-grants-1982_03
特許番号
US04317830

反応ノート

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