反応式
[CH2:1]([O:3]C=CC#N)[CH3:2].[Na].[CH2:9]([O:11][C:12](=[O:16])[CH:13]=[CH:14][OH:15])[CH3:10].Cl.[CH2:18](O)[CH3:19]>>[CH2:9]([O:11][C:12](=[O:16])[CH2:13][CH:14]([O:3][CH2:1][CH3:2])[O:15][CH2:18][CH3:19])[CH3:10]参加物
6
実験手順
A complicated synthesis of β-ethoxyacrylonitrile (I) by a plurality of steps has been described, which entails the tranposition of the sodium salt of β-hydroxyacrylic acid ethyl ester with ethanol in the presence of HCl to form β,β-diethoxypropionic acid ethyl ester, the preparation of the amide by reaction with ammonia, and further dehydration with phosphorus pentoxide, β-ethoxyacrylonitrile (I) being formed as a by-product (S. M. McElvain and R. L. Clark, J. Amer. Chem. Soc., 69, (1947) 2657).
出典と根拠
- ORDレコード
- ord-553a0bb51cb842d09bf2ea57c571491d
- 出典データセット
- uspto-grants-1982_03
- 特許番号
- US04319024
関連ノート
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