Potassium Nitrate → HCID 178513826、化合物
反応式
[OH:1][C:2]1[C:3]([C:8]([NH2:10])=[O:9])=[N:4][CH:5]=[CH:6][N:7]=1.[N+:11]([O-])([O-:13])=[O:12].[K+]>S(=O)(=O)(O)O.O>[OH:1][C:2]1[C:3]([C:8]([NH2:10])=[O:9])=[N:4][C:5]([N+:11]([O-:13])=[O:12])=[CH:6][N:7]=1参加物
5
反応条件
- 温度
- 40 °C
実験手順
In 24 mL of concentrated sulfuric acid is suspended 4.00 g of 3-hydroxy-2-pyrazinecarboxamide. To the suspension is added 3.09 g of potassium nitrate under ice-cooling. The resulting mixture is stirred at 40° C. for 3 hours. The reaction mixture is poured into 240 mL of water, and the deposited crystals are collected by filtration. The crystals thus obtained are suspended in 80 mL of water and heated under reflux for 30 minutes. After cooling, the crystals are collected by filtration to obtain 2.45 g of 3-hydroxy-6-nitro-2-pyrazinecarboxamide.
後処理
- temperaturecooling
- filtrationthe deposited crystals are collected by filtration
- customThe crystals thus obtained
- temperatureheated
- temperatureunder reflux for 30 minutes
- temperatureAfter cooling
- filtrationthe crystals are collected by filtration
出典と根拠
- ORDレコード
- ord-d95554f558404ca4a7162380e1809bbf
- 出典データセット
- uspto-grants-2012_10
- 特許番号
- USRE043748E1
反応ノート
読み込み中…