Nitrogen → HCID 66928589、化合物
反応式
N#N.[N+:3]([C:6]1[CH:7]=[N:8][N:9]([CH2:11][C:12]2[O:16][N:15]=[C:14]([CH:17]([OH:19])[CH3:18])[CH:13]=2)[CH:10]=1)([O-:5])=[O:4]>C(Cl)Cl.O=[Mn]=O>[N+:3]([C:6]1[CH:7]=[N:8][N:9]([CH2:11][C:12]2[O:16][N:15]=[C:14]([C:17](=[O:19])[CH3:18])[CH:13]=2)[CH:10]=1)([O-:5])=[O:4]参加物
5
実験手順
In a flame dried round-bottomed flask equipped with a magnetic stir bar and under inert atmosphere (N2), a solution of 1-[5-(4-nitro-pyrazol-1-ylmethyl)-isoxazol-3-yl]-ethanol (435 mg, 1.83 mmol) in CH2Cl2 (8.0 mL) was treated at rt with MnO2 (1.32 g, 13.70 mmol) and the reaction mixture was stirred for 16 h at rt before being filtered through Celite. The solvent was removed under reduced pressure to give the title compound. LC-MS-conditions 02: tR=0.87 min.
後処理
- filtrationbefore being filtered through Celite
- customThe solvent was removed under reduced pressure
出典と根拠
- ORDレコード
- ord-ab2ab2eae83b4ad9b05176c2b6751fc5
- 出典データセット
- uspto-grants-2012_10
- 特許番号
- US08288419B2
反応ノート
読み込み中…