1,1'-Carbonyldiimidazole → HCID 86649581、化合物
反応式
[CH:1]1[N:5]=[CH:4][N:3]([C:6](N2C=NC=C2)=[O:7])[CH:2]=1.[CH3:13][C:14]1[N:15]=[C:16]([NH2:31])[S:17][C:18]=1[C:19]1[N:20]=[C:21]([C:24]2([C:27]([F:30])([F:29])[F:28])[CH2:26][CH2:25]2)[S:22][CH:23]=1>C(Cl)Cl>[CH3:13][C:14]1[N:15]=[C:16]([NH:31][C:6]([N:3]2[CH:2]=[CH:1][N:5]=[CH:4]2)=[O:7])[S:17][C:18]=1[C:19]1[N:20]=[C:21]([C:24]2([C:27]([F:30])([F:29])[F:28])[CH2:25][CH2:26]2)[S:22][CH:23]=1参加物
4
実験手順
CDI (0.13 g) was added to a stirred solution of 4′-methyl-2-(1-trifluoromethyl-cyclopropyl)-[4,5]bithiazolyl-2′-ylamine (Step 10.2) (0.16 g) in CH2Cl2 (5 mL) at rt. The reaction mixture was then stood for 3 h at 25° C. and the title compound isolated by filtration.
出典と根拠
- ORDレコード
- ord-dbc65e0e25174d29bdec4357ce778c8c
- 出典データセット
- uspto-grants-2012_10