Chloroacetaldehyde → HCID 21412824、化合物

HRID 2071206ノート

反応式

HRID 2071206 の反応式
[CH2:1]([C:3]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH3:11])[C:4]=1[NH2:5])[CH3:2].Cl[CH2:13][CH:14]=[O:15].C(=O)([O-])[O-].[Na+].[Na+]>>[CH2:1]([C:3]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH3:11])[C:4]=1[NH:5][CH2:13][CH:14]=[O:15])[CH3:2]

参加物

4

反応物 3

HCID 33ChloroacetaldehydeHCID 10340Sodium CarbonateHCID 100805692-Ethyl-6-methoxyaniline

生成物 1

HCID 21412824HCID 21412824、化合物

反応条件

温度
150 °C

実験手順

2-Ethyl-6-methoxyaniline (0.3 mole), the dimethyl acetal of 2-chloroacetaldehyde (0.3 mole) and sodium carbonate (20 grams) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture is heated at about 150° C. for a period of about 8 hours. After this time the mixture is filtered and the filtrate is distilled to yield the desired product the dimethyl acetal of 2-(2-ethyl-6-methoxyanilino)acetaldehyde.

後処理

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. filtrationAfter this time the mixture is filtered
  4. distillationthe filtrate is distilled

出典と根拠

ORDレコード
ord-b3e9fd853fad4d26bfd1f81f785924c3
出典データセット
uspto-grants-1977_09
特許番号
US04046554

反応ノート

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