Dimethyl acetylenedicarboxylate → HCID 86735049、化合物
反応式
[NH2:1][C:2]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([Cl:13])[CH:9]=2)[O:4][CH:3]=1.[C:14]([C:20]([O:22][CH3:23])=[O:21])#[C:15][C:16]([O:18][CH3:19])=[O:17]>CO>[Cl:13][C:8]1[CH:7]=[CH:6][C:5]2[O:4][CH:3]=[C:2]([NH:1][C:15](=[CH:14][C:20]([O:22][CH3:23])=[O:21])[C:16]([O:18][CH3:19])=[O:17])[C:11](=[O:12])[C:10]=2[CH:9]=1参加物
4
実験手順
A mixture of 3-amino-6-chlorochromone (8 g, 0.041 mole) and dimethyl acetylenedicarboxylate (10.5 g, 0.074 mole) in methanol (150 ml) was stirred at room temperature for 2 days. The product was filtered off and washed with methanol. Recrystallization from ethyl acetate gave yellow crystals (11 g, 80%), m.p. 158°-160°.
後処理
- filtrationThe product was filtered off
- washwashed with methanol
- customRecrystallization from ethyl acetate
出典と根拠
- ORDレコード
- ord-fd6038b7847d4d47bbe5df8b28986452
- 出典データセット
- uspto-grants-1977_09
- 特許番号
- US04046769
反応ノート
読み込み中…