Sodium Hydroxide → Urea, (1,2,3,4-tetrahydro-4-oxo-1-naphthalenyl)-

HRID 2072371ノート

反応式

HRID 2072371 の反応式
C([NH:9][C:10]([NH:12][CH:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[C:16](=[O:23])[CH2:15][CH2:14]1)=[O:11])(=O)C1C=CC=CC=1.[OH-].[Na+]>>[O:23]=[C:16]1[C:17]2[C:22](=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:13]([NH:12][C:10]([NH2:9])=[O:11])[CH2:14][CH2:15]1

参加物

3

反応物 2

HCID 14798Sodium HydroxideHCID 205373021-Benzoyl-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)urea

生成物 1

HCID 3628438Urea, (1,2,3,4-tetrahydro-4-oxo-1-naphthalenyl)-収率 72.7%

実験手順

A mixture of 1-benzoyl-3-(1,2,3,4-tetrahydro-4-oxo- 1-naphthyl)urea (3.8 g) and aqueous sodium hydroxide (2N; 38 ml) is stirred and heated at reflux for 70 minutes. The mixture is then cooled in ice and the product is collected and washed with water to afford 1.83 g of the title compound, m.p. 212° to 215° C.

後処理

  1. temperatureheated
  2. temperatureat reflux for 70 minutes
  3. temperatureThe mixture is then cooled in ice
  4. customthe product is collected
  5. washwashed with water

出典と根拠

ORDレコード
ord-3b6e8fcee1744a7f8d65b6a9e6f652f4
出典データセット
uspto-grants-1977_09
特許番号
US04051183

反応ノート

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