Cyclohexylamine → N-(4-chlorophenyl)-N'-cyclohexylthiourea
反応式
[CH:1]1([NH2:7])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]=[C:16]=[S:17])=[CH:11][CH:10]=1>C(Cl)(Cl)Cl>[CH:1]1([NH:7][C:16]([NH:15][C:12]2[CH:13]=[CH:14][C:9]([Cl:8])=[CH:10][CH:11]=2)=[S:17])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1参加物
4
実験手順
To a solution of cyclohexylamine (1.75 g.) in chloroform (15 ml.) was added dropwise with stirring a solution of p-chlorophenylisothiocyanate (3.0 g.) in chloroform (15 ml.) at room temperature. After stirring 3 hours, the white solid was filtered off, washed with a little CHCl3 and recrystallised from toluene to give 1-cyclohexyl-3-(p-chlorophenyl)thiourea, m.p. 179°-180°.
後処理
- filtrationthe white solid was filtered off
- washwashed with a little CHCl3
- customrecrystallised from toluene
出典と根拠
- ORDレコード
- ord-a673fd332d83447d8cb2b4f49c587923
- 出典データセット
- uspto-grants-1977_09
- 特許番号
- US04051256
反応ノート
読み込み中…