Hydrogen Bromide → 3,3'-Difluoro-4,4'-dihydroxybiphenyl
反応式
[F:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:15]=[CH:14][C:13]([O:16]C)=[C:12]([F:18])[CH:11]=2)[CH:5]=[CH:6][C:7]=1[O:8]C.Br>O1CCOCC1>[F:1][C:2]1[CH:3]=[C:4]([C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[C:12]([F:18])[CH:11]=2)[CH:5]=[CH:6][C:7]=1[OH:8]参加物
4
実験手順
10.0 g of 3,3'-difluoro-4,4'-dimethoxybiphenyl was dissolved in 150 ml of dioxane, and 150 ml of 48% hydrobromic acid was added. The mixture was heated under reflux for 50 hours. After the reaction, the reaction mixture was subjected to evaporation under reduced pressure. The residue was fully washed with water to obtain the desired 3,3'-difluoro-4,4'-dihydroxybiphenyl.
後処理
- temperatureThe mixture was heated
- temperatureunder reflux for 50 hours
- customAfter the reaction
- customthe reaction mixture was subjected to evaporation under reduced pressure
- washThe residue was fully washed with water
出典と根拠
- ORDレコード
- ord-22eec997dd984271a95b2777c6cc5e19
- 出典データセット
- uspto-grants-1990_04
- 特許番号
- US04914224
反応ノート
読み込み中…