Acetic Anhydride → HCID 53739244、化合物

HRID 2072840

反応式

HRID 2072840 の反応式
[Cl:1][C:2]1[CH:12]=[C:11]([Cl:13])[CH:10]=[CH:9][C:3]=1[C:4]([CH2:6][C:7]#[N:8])=[O:5].[C:14]([O:17][C:18](=O)C)(=O)C>>[Cl:1][C:2]1[CH:12]=[C:11]([Cl:13])[CH:10]=[CH:9][C:3]=1[C:4]([C:6](=[CH:14][O:17][CH3:18])[C:7]#[N:8])=[O:5]

参加物

3

反応物 2

HCID 7918Acetic AnhydrideHCID 136307283-(2,4-Dichlorophenyl)-3-oxopropanenitrile

生成物 1

HCID 53739244HCID 53739244、化合物収率 104.5%

反応条件

温度
150 °C

実験手順

A mixture of 8.8 g of 2,4-dichloro-benzoylacetonitrile, 69.2 g of methyl o-formate and 10.5 g of acetic anhydride is refluxed at a bath temperature of 150° C. for 3 hours. The volatile constituents are then distilled off in vacuo and finally under a fine vacuum at a bath temperature of 120° C. 11 g of 2-(2,4-dichloro-benzoyl)-3-methoxy-acrylonitrile are obtained as a viscous oil.

後処理

  1. distillationThe volatile constituents are then distilled off in vacuo and finally under a fine vacuum at a bath temperature of 120° C

出典と根拠

ORDレコード
ord-391df9ca579547fd8fe272604eefc0dd
出典データセット
uspto-grants-1990_04
特許番号
US04914228

関連ノート

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