Benzoyl Peroxide → HCID 19858052、化合物

HRID 2073388ノート

反応式

HRID 2073388 の反応式
[CH3:1][C:2]1([CH3:19])[C:6](=[O:7])[O:5][C:4]2[CH:8]=[CH:9][C:10]3[C:15]([C:3]1=2)=[CH:14][C:13]([CH3:16])=[C:12]([C:17]#[N:18])[CH:11]=3.[Br:20]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:20][CH2:16][C:13]1[CH:14]=[C:15]2[C:10]([CH:9]=[CH:8][C:4]3[O:5][C:6](=[O:7])[C:2]([CH3:19])([CH3:1])[C:3]=32)=[CH:11][C:12]=1[C:17]#[N:18]

参加物

5

反応物 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 19858070HCID 19858070、化合物

生成物 1

HCID 19858052HCID 19858052、化合物

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A mixture of 1,2-dihydro-1,1,8-trimethyl-2-oxonaphtho[2,1-b]furan-7-carbonitrile, (0.25 g), N-bromosuccinimide (0.2 g), benzoyl peroxide (0.01 g) and carbon tetrachloride (40 ml) was stirred under reflux for 24 h. The reaction mixture was cooled, washed with water, dried and evaporated to dryness under reduced pressure, to give the required starting material, 8-bromomethyl-1,2-dihydro-1,1-dimethyl-2-oxonaphtho[2,1-b]furan-7-carbonitrile, which was used without further purification.

後処理

  1. temperatureunder reflux for 24 h
  2. temperatureThe reaction mixture was cooled
  3. washwashed with water
  4. customdried
  5. customevaporated to dryness under reduced pressure

出典と根拠

ORDレコード
ord-d6e88b7ab9ea4d279e7cdea699f3ef18
出典データセット
uspto-grants-1990_04
特許番号
US04916148

反応ノート

読み込み中…