Thionyl Chloride → alpha-(3-Chloromethylphenoxy)acetonitrile
反応式
O[CH2:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][CH:12]=1)[O:6][CH2:7][C:8]#[N:9].S(Cl)([Cl:15])=O>C(OCC)C.CN(C)C=O>[Cl:15][CH2:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][CH:12]=1)[O:6][CH2:7][C:8]#[N:9]参加物
5
実験手順
α-(3-Hydroxymethylphenoxy)acetonitrile (0.055 mol) in diethylether (150 ml) is stirred with thionyl chloride (0.060 ml) and a few drops of dimethylformamide at 40° C. for 1 hr. The solution is washed with water and brine, then evaporated to give α-(3-chloromethylphenoxy)acetonitrile as a yellow oil which is used directly in the next step.
後処理
- washThe solution is washed with water and brine
- customevaporated
出典と根拠
- ORDレコード
- ord-66aa89bd7e174ccc938c806af75fcc0f
- 出典データセット
- uspto-grants-1990_04
- 特許番号
- US04920132
反応ノート
読み込み中…