Bromine → 2-Bromo-6-(2,4-dichloro-phenyl)-cyclohexanone
反応式
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]1[CH2:14][CH2:13][CH2:12][CH2:11][C:10]1=[O:15].[Br:16]Br>C(Cl)(Cl)Cl>[Br:16][CH:11]1[CH2:12][CH2:13][CH2:14][CH:9]([C:3]2[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=2[Cl:1])[C:10]1=[O:15]参加物
4
実験手順
2-(2,4-Dichloro-phenyl)-cyclohexanone (50 mg, 0.21 mmol) was dissolved in chloroform (1 mL). To this solution bromine (34.5 mg, 0.22 mmol) in chloroform (0.5 mL) was added drop wise at room temperature. The reaction was stirred for 1½ hours at room temperature. The solvent was removed under reduced pressure to yield the crude title compound (79 mg) which was used directly in the next step without further purification.
後処理
- customThe solvent was removed under reduced pressure
出典と根拠
- ORDレコード
- ord-e58ec677299a415091bce371896f7ad0
- 出典データセット
- uspto-grants-2011_04
- 特許番号
- US07923450B2
反応ノート
読み込み中…