tert-Butoxy bis(dimethylamino)methane → HCID 67096291、化合物

反応式

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]2([CH2:16][CH2:17][CH3:18])[CH2:14][CH2:13][CH2:12][CH2:11][C:10]2=[O:15])[CH:6]=[CH:7][CH:8]=1.C(O[CH:24](N(C)C)[N:25]([CH3:27])[CH3:26])(C)(C)C>>[CH3:24][N:25]([CH3:27])[CH:26]=[C:11]1[C:10](=[O:15])[C:9]([C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=2)([CH2:16][CH2:17][CH3:18])[CH2:14][CH2:13][CH2:12]1

参加物

反応物 2

HCID 79885tert-Butoxy bis(dimethylamino)methane

HCID 670959582-(3-Methoxy-phenyl)-2-propyl-cyclohexanone

生成物 1

HCID 67096291HCID 67096291、化合物

実験手順

2-(3-Methoxy-phenyl)-2-propyl-cyclohexanone (101 mg, 0.41 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (124 mg) as red oil which was used directly in the next step. MS ISP (m/e): 302.1 [(M+H)+].

出典と根拠

ORDレコード: ord-6faab3625edf4a9cb13e47dd56fbb6a1
出典データセット: uspto-grants-2011_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07923450B2

反応ノート

読み込み中…

参加物