tert-Butoxy bis(dimethylamino)methane → HCID 67096114、化合物

HRID 2076098ノート

反応式

HRID 2076098 の反応式
[OH:1][C:2]1([C:9]2[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=2)[CH2:7][CH2:6][CH2:5][CH2:4][C:3]1=[O:8].C(O[CH:20](N(C)C)[N:21]([CH3:23])[CH3:22])(C)(C)C>>[CH3:20][N:21]([CH3:23])/[CH:22]=[C:4]1\[CH2:5][CH2:6][CH2:7][C:2]([OH:1])([C:9]2[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=2)[C:3]\1=[O:8]

参加物

3

反応物 2

HCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 448908492-Hydroxy-2-pyridin-3-yl-cyclohexanone

生成物 1

HCID 67096114HCID 67096114、化合物

実験手順

2-Hydroxy-2-pyridin-3yl-cyclohexanone (394 mg, 2 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (582 mg) as a brown oil which was used directly in the next step. MS ISP (m/e): 247.2 (100) [(M+H)+].

出典と根拠

ORDレコード
ord-af9f0c7445964dd0b6ca72bc6b48a81b
出典データセット
uspto-grants-2011_04
特許番号
US07923450B2

反応ノート

読み込み中…