Thionyl Chloride → 2-(3-Chlorophenyl)-2-methylpropanoyl chloride

反応式

[Cl:1][C:2]1[CH:3]=[C:4]([C:8]([CH3:13])([CH3:12])[C:9](O)=[O:10])[CH:5]=[CH:6][CH:7]=1.S(Cl)([Cl:16])=O>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]([CH3:13])([CH3:12])[C:9]([Cl:16])=[O:10])[CH:5]=[CH:6][CH:7]=1

参加物

反応物 2

HCID 24386Thionyl Chloride

HCID 155826442-(3-Chlorophenyl)-2-methylpropanoic acid

生成物 1

HCID 139875312-(3-Chlorophenyl)-2-methylpropanoyl chloride

実験手順

2-(3-Chlorophenyl)-2-methylpropanoic acid (5.7 g, 28.7 mmol) was stirred in thionyl chloride (100 mL) for 2 hours at reflux. The thionyl chloride was removed under vacuum to give the product (5.69 g).

後処理

temperatureat reflux
customThe thionyl chloride was removed under vacuum

出典と根拠

ORDレコード: ord-e875b7ed7d81462790be6475de18cdd0
出典データセット: uspto-grants-2011_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07928139B2

反応ノート

読み込み中…