Thionyl Chloride → 2-Benzyloxy-ethanesulfonyl chloride
反応式
[CH2:1]([O:8][CH2:9][CH2:10][S:11]([OH:14])(=O)=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:17])=O>CN(C)C=O>[CH2:1]([O:8][CH2:9][CH2:10][S:11]([Cl:17])(=[O:14])=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
4
実験手順
To a 2-(benzyloxy)ethanesulfonic acid (4.0 g) was added thionyl chloride (13.5 ml) dropwise at ambient temperature for 15 minutes and the mixture was stirred at the same temperature for 10 minutes. To the mixture was added dropwise N,N-dimethylformamide (0.072 ml) at ambient temperature. The mixture was stirred at the same temperature for 20 minutes and refluxed for 1 hour. After cooling down to room temperature, the mixture was evaporated under reduced pressure to give 2-(benzyloxy)ethanesulfonyl chloride (4.1 g).
後処理
- stirringThe mixture was stirred at the same temperature for 20 minutes
- temperaturerefluxed for 1 hour
- customthe mixture was evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-8da05fb1ee3346c88a79edd938e9d889
- 出典データセット
- uspto-grants-2011_04
- 特許番号
- US07928264B2
反応ノート
読み込み中…