Cyclopentanone → 1-(Diethylamino)cyclopentanecarbonitrile
反応式
Cl.[CH2:2]([NH:4][CH2:5][CH3:6])[CH3:3].[C:7]1(=O)[CH2:11][CH2:10][CH2:9][CH2:8]1.[C-]#N.[K+].[CH3:16][N:17](C)C1(C#N)CCCC1>O>[CH2:2]([N:4]([CH2:5][CH3:6])[C:7]1([C:16]#[N:17])[CH2:11][CH2:10][CH2:9][CH2:8]1)[CH3:3]参加物
6
実験手順
The title compound (2.06 g, 62%) was prepared from diethylamine hydrochloride (2.14 g, 20 mmol), cyclopentanone (1.68 g, 20 mmol) and potassium cyanide (1.30 g, 20 mmol) in water (10 ml) in a similar manner to that described in D1. 1H NMR (CDCl3) δ: 1.11 (6H, t, J=7 Hz), 1.78-1.88 (6H, m), 2.22 (2H, m), 2.71 (4H, q, J=7 Hz).
出典と根拠
- ORDレコード
- ord-10ca5a0bc6414f21970b59dd43514c14
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07745642B2
反応ノート
読み込み中…