Water → 2-(3-Pentafluorosulfanylphenyl)isoindole-1,3-dione

HRID 2080930ノート

反応式

HRID 2080930 の反応式
[F:1][S:2]([F:13])([F:12])([F:11])([F:10])[C:3]1[CH:4]=[C:5]([NH2:9])[CH:6]=[CH:7][CH:8]=1.[C:14]1(=O)[O:19][C:17](=[O:18])[C:16]2=[CH:20][CH:21]=[CH:22][CH:23]=[C:15]12.O>C(O)(=O)C>[F:1][S:2]([F:10])([F:11])([F:12])([F:13])[C:3]1[CH:4]=[C:5]([N:9]2[C:17](=[O:18])[C:16]3[C:15](=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:14]2=[O:19])[CH:6]=[CH:7][CH:8]=1

参加物

5

反応物 3

HCID 962WaterHCID 6811Phthalic AnhydrideHCID 27791883-(Pentafluoro-lambda6-sulfanyl)aniline

生成物 1

HCID 596421532-(3-Pentafluorosulfanylphenyl)isoindole-1,3-dione

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

15 g (68.44 mmol) of 3-pentafluorosulfanylphenylamine was suspended with 10.14 g (68.44 mmol) of phthalic anhydride in 40 ml of a acetic acid and boiled under reflux for 2 h. The cool reaction mixture was admixed with 400 ml of water, heated in an ultrasound bath for 30 min and filtered. The residue was washed with water and subsequently with a little ethanol and dried under reduced pressure. 2-(3-Pentafluorosulfanylphenyl)isoindole-1,3-dione was obtained with a melting point of 188-190° C.

後処理

  1. temperatureunder reflux for 2 h
  2. customThe cool reaction mixture
  3. temperatureheated in an ultrasound bath for 30 min
  4. filtrationfiltered
  5. washThe residue was washed with water and subsequently with a little ethanol
  6. customdried under reduced pressure

出典と根拠

ORDレコード
ord-242967847e064915a96e1e89d5d29bbc
出典データセット
uspto-grants-2011_04
特許番号
US07932416B2

反応ノート

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