2-Fluoroaniline → HCID 3265055、化合物

反応式

[F:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].[C:9]1(=O)[CH2:14][CH2:13][CH2:12][C:11](=[O:15])[CH2:10]1>>[F:1][C:2]1[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=1[NH:4][C:9]1[CH2:14][CH2:13][CH2:12][C:11](=[O:15])[CH:10]=1

参加物

反応物 2

HCID 95842-Fluoroaniline

HCID 104341,3-Cyclohexanedione

生成物 1

HCID 3265055HCID 3265055、化合物収率 80.9%

実験手順

2-Fluoroaniline (10 g) and cyclohexane-1,3-dione (10 g) were heated together under nitrogen at 120° for 1 h. The cooled mixture was triturated with ether and filtered to give the title compound (14.8 g), m.p. 116°-118°.

後処理

customThe cooled mixture was triturated with ether
filtrationfiltered

出典と根拠

ORDレコード: ord-4ef68f3cc0604ca9a48149c6cf059e35
出典データセット: uspto-grants-1993_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05183820

反応ノート

読み込み中…