Hydrochloric Acid → 4-Biphenylyl benzoate

HRID 2082109ノート

反応式

HRID 2082109 の反応式
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:13][CH:12]=1.Cl.O>N1C=CC=CC=1>[C:1]([O:10][C:11]1[CH:12]=[CH:13][C:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:15][CH:16]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 71034-HydroxybiphenylHCID 7412Benzoyl chloride

生成物 1

HCID 2317434-Biphenylyl benzoate収率 94%

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

128 ml benzoyl chloride is dripped into a solution of 170 g 4-hydroxybiphenyl in 500 ml pyridine, at 20° C.; subsequently, the reaction mixture is heated under reflux for 30 min. After cooling, the reaction mixture is mixed with a solution of 500 ml concentrated hydrochloric acid and 750 ml water. The remaining precipitate is filtered off, washed neutral with water, dried and recrystallized from n-butanol (melting point: 150° C.); yield: 94%.

後処理

  1. temperaturesubsequently, the reaction mixture is heated
  2. temperatureunder reflux for 30 min
  3. temperatureAfter cooling
  4. filtrationThe remaining precipitate is filtered off
  5. washwashed neutral with water
  6. customdried
  7. customrecrystallized from n-butanol (melting point: 150° C.)

出典と根拠

ORDレコード
ord-0c10c08e9eb6412ab234c4568d03deef
出典データセット
uspto-grants-1993_02
特許番号
US05187237

反応ノート

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