Nitric Acid → HCID 20360787、化合物

反応式

[OH:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][CH:14]=1)[C:5]([CH2:7][CH2:8][C:9]([OH:11])=[O:10])=[O:6].[N+:15]([O-])([OH:17])=[O:16]>>[OH:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][C:14]=1[N+:15]([O-:17])=[O:16])[C:5]([CH2:7][CH2:8][C:9]([OH:11])=[O:10])=[O:6]

参加物

反応物 2

HCID 944Nitric Acid

HCID 2703964-(3-Hydroxyphenyl)-4-oxobutanoic acid

生成物 1

HCID 20360787HCID 20360787、化合物

実験手順

3-(3-Hydroxybenzoyl)propionic acid was added in portions to well stirred fuming nitric acid at -15° C. The resultant mixture was stirred a further 10 minutes in the cold then poured into ice-water. The crude product was triturated with methanol to give 3-(3-hydroxy-4-nitrobenzoyl)propionic acid, which after recrystallisation from water had m.p. 158° - 160.3° C (Found: C, 50.25; H, 3.75; N, 5.88; M+, 239 C10H9NO6 requires: C, 50.21; H, 3.79; N, 5.86%; M, 239)

後処理

customThe crude product was triturated with methanol

出典と根拠

ORDレコード: ord-494e5732f498415ebdff14c956876c20
出典データセット: uspto-grants-1978_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04082843

反応ノート

読み込み中…

参加物