Sodium borohydride → HCID 178466054、化合物
反応式
[C:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[O:10][CH:9]=[C:8]([C:14]1[NH:18][N:17]=[N:16][N:15]=1)[C:7]2=[O:19])(=[O:3])[CH3:2].[BH4-].[Na+]>CO>[OH:3][CH:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[O:10][CH:9]=[C:8]([C:14]1[NH:18][N:17]=[N:16][N:15]=1)[C:7]2=[O:19])[CH3:2]参加物
4
実験手順
To a suspension of 0.128 part of 6-acetyl-3-(1H-tetrazol-5-yl)chromone in 5 parts by volume of methanol is added under stirring 0.020 part of sodium borohydride. The resulting mixture is stirred at room temperature for 2 minutes and then refluxed for 2 minutes. The solvent is distilled off and to the residue is added 10 parts by volume of 1N-hydrochloric acid. The resulting precipitates are recovered by filtration and recrystallized twice from ethanol to obtain 0.013 part of 6-(1-hydroxyethyl)-3-(1H-tetrazol-5-yl)chromone as colorless crystals melting at 234°-236° C(decomposition with foaming).