Thiazolidine → (S)-N-{2-[2-Amino-3-oxo-3-(1,3-thiazolidin-3-yl)propylthio]-ethyl}-methanesulphonamide hydrochloride
反応式
C(OC([NH:11][CH2:12][CH2:13][S:14][CH2:15][C@H:16]([C:25]([OH:27])=O)[NH:17]C(OC(C)(C)C)=O)=O)C1C=CC=CC=1.[CH3:28][S:29]([Cl:32])(=[O:31])=[O:30].[S:33]1[CH2:37][CH2:36][NH:35][CH2:34]1>>[ClH:32].[NH2:17][C@@H:16]([C:25](=[O:27])[N:35]1[CH2:36][CH2:37][S:33][CH2:34]1)[CH2:15][S:14][CH2:13][CH2:12][NH:11][S:29]([CH3:28])(=[O:31])=[O:30]参加物
4
実験手順
Starting from (S)-3-(2-{[benzyloxycarbonyl]-amino}-ethylthio)-N-(tert-butyloxy-carbonyl)-alanine, methanesulphonyl chloride and 1,3-thiazolidine, the expected product is obtained according to the procedure described in Example 37.
出典と根拠
- ORDレコード
- ord-efa9d10bedac44deaf25d2cb35396961
- 出典データセット
- uspto-grants-2004_04
- 特許番号
- US06716843B2
反応ノート
読み込み中…