3-(Trifluoromethyl)benzoyl chloride → N'-(2-phenoxypyridine-3-carbonyl)-3-(trifluoromethyl)benzhydrazide

HRID 2084258ノート

反応式

HRID 2084258 の反応式
[O:1]([C:8]1[N:17]=[CH:16][CH:15]=[CH:14][C:9]=1[C:10]([NH:12][NH2:13])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:18][C:19]([F:30])([F:29])[C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][CH:28]=1)[C:23](Cl)=[O:24]>N1C=CC=CC=1>[O:1]([C:8]1[C:9]([C:10]([NH:12][NH:13][C:23](=[O:24])[C:22]2[CH:26]=[CH:27][CH:28]=[C:20]([C:19]([F:18])([F:29])[F:30])[CH:21]=2)=[O:11])=[CH:14][CH:15]=[CH:16][N:17]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 752573-(Trifluoromethyl)benzoyl chlorideHCID 27976852-Phenoxynicotinohydrazide

生成物 1

HCID 2797700N'-(2-phenoxypyridine-3-carbonyl)-3-(trifluoromethyl)benzhydrazide

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

Alternatively, as shown in scheme 2, reaction of 2-phenoxy-nicotinic acid hydrazide with 3-trifluoromethyl-benzoyl chloride in the presence of a base such as pyridine produced N′-(2-phenoxypyridine-3-carbonyl)-3-(trifluoromethyl)benzhydrazide as the product.

出典と根拠

ORDレコード
ord-1bf87609dea646c894905922e97c9cf7
出典データセット
uspto-grants-2004_04
特許番号
US06716859B2

反応ノート

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