関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Mesitylene | HCID 7947 | — |
| 反応物 | 4-Chloro-3-oxobutyryl chloride | HCID 3016262 | — |
| 触媒 | Scandium(III) triflate | HCID 2734571 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | gamma-Chloroacetoacetylmesitylene | HCID 22734549 | — |
反応手順
4-Chloroacetoacetyl chloride (35% strength solution in dichloromethane, 26.2 g, 59 mmol), mesitylene (7.4 g, 59 mmol, and scandium trifluoro-methanesulphonate (2.6 g, 5.1 mmol) were introduced at 20° C. The reaction mixture was then stirred at 24° C. for a total of 2 days. It was then hydrolysed with water (10 ml). The organic phase was concentrated, and the residue was dried in a high vacuum. 9.1 g of crude product were obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06716999B2 |
|---|
| 出典データセット | uspto-grants-2004_04 |
|---|
| ORD ID | ord-c093ba90add34e0090fee5360639f16b |
|---|
| 出典メモ | uspto-grants-2004_04 |
|---|
